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Trimix Intracavernosal Self-Injection Guide

Step-by-step instructions for properly injecting Trimix into the penis, including preparation, dosage, injection site selection, and safety precautions.

So you have to inject Trimix...

So you have to inject Trimix...

STEP 01:

GATHER SUPPLIES

  • Alcohol swabs
  • Sterile syringe with needle
  • Medication vial (keep in original light-protective container)
  • Sharps container for safe disposal
  • Rx label with dosage instructions

🧊 If your medication was shipped frozen, allow it to thaw naturally. Do not heat the vial.

STEP 02:

PREPARE YOURSELF

  • Wash hands thoroughly with soap and water, then dry.
  • Sit upright or recline slightly in a comfortable position.
  • Select your injection site:
    • Between the base and mid-shaft of the penis.
    • Use the 10 to 2 o’clock areas on either side. Avoid the top, bottom, and visible blood vessels.
  • Gently pull the head of the penis to one side.
  • Clean the injection site with an alcohol swab and allow it to dry completely to avoid stinging.
STEP 03:

PREPARE THE MEDICINE

  • Open an alcohol swab and clean the rubber stopper on the vial. Let it air dry.
  • Remove the needle cover from the syringe.
  • Draw in air equal to your prescribed dose (e.g., 0.2 mL).
  • Insert the needle straight into the rubber stopper and inject the air to equalize pressure.
  • Turn the vial upside down with the needle still inserted.
  • Slowly pull back the plunger to draw up your dose.
  • Tap the syringe to remove any air bubbles, then push the plunger to the correct dose.
  • Remove the syringe from the vial carefully, without touching the needle.
STEP 04:

ADMINISTER THE MEDICATION

  • Grasp the head of the penis and pull it straight out.
  • Hold the syringe at a 90-degree angle and inject into the side of the penis with steady pressure.
  • Inject medication over about 4 seconds.
  • Withdraw the needle gently and immediately apply pressure to the site using an alcohol swab for 1–2 minutes (3–5 minutes if taking aspirin).
  • Alternate injection sites each time.
  • Safely dispose of the syringe and needle in a sharps container.

⚠️ Important Guidelines

  • Only use the dose prescribed by your doctor.
  • Limit injections to 3 times per week and space doses at least 24 hours apart.
  • If erection lasts longer than 2 hours, take 30 mg pseudoephedrine and apply an ice pack.
  • If still erect after 3 hours, contact your doctor or visit the ER immediately.
  • Discard vial 28 days after first use or by labeled expiration—whichever is sooner.

Possible Side Effects

  • Penile pain
  • Bruising or burning at the injection site
  • Headache or dizziness
  • Prolonged erection (priapism)
  • Swelling, curvature, or tenderness—contact your doctor if this occurs

Frequently Asked Questions