The image shown is for illustrative purposes only and does not represent the actual appearance of your specific compounded medication.
AquaBiome
When applied topically, this GHK-Cu preparation is designed to support the skin’s natural collagen and maintain a healthy-looking appearance. It targets the appearance of fine lines and wrinkles while helping to soothe and calm the skin. This individualized formulation aids in maintaining a radiant complexion as part of a provider-guided care plan.
GHK-Cu Acetate
AquaBiome (GHK-Cu) Cream
Cleanse the face thoroughly and pat dry. Apply a small amount to fingertips and gently massage the product onto the face and neck in upward motions.
- May use morning and night for best outcomes.
- Follow with a moisturizer and broad-spectrum sunscreen during the day.
IMPORTANT INFORMATION ABOUT COMPOUNDED MEDICATIONS
This medication has been compounded (custom-prepared) by a pharmacy. Compounded medications are specially prepared for individual patient needs based on a valid prescription from a prescribing healthcare practitioner and, as such, are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. Compounded drugs are intended for patients whose prescriber has determined their medical needs are not met by an available FDA-approved drug. These statements have not been evaluated by the FDA.
This compounded preparation:
- Has not been approved by the FDA
- Has not undergone FDA review for safety, effectiveness, or quality
- Is prepared specifically for you based on your prescriber's order
- Individual outcomes may vary
Dosing is determined by the prescribing provider based on patient-specific factors. Always follow your healthcare provider's instructions. Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications. This medication should be prescribed and monitored by a licensed healthcare professional familiar with the condition being addressed and the specific applications of the medication.
This compounded medication is only available when the commercially available product is unavailable or when a prescriber determines that there is a clinically significant difference for the patient.
Medicine Information
Some of the potential benefits include but are not limited to:
- Addresses inflammation2,3
- Supports skin repair function, regeneration, and overall skin health1-3
- Promote collagen production1,2
- Encourage formation of new blood vessels2,3
- Promote skin firmness, elasticity, and resilience1,2
- Help minimize the appearance of fine lines and support skin texture1
- Provide deep hydration and moisture retention1
- Contribute to the appearance of smooth, radiant complexion1,2
Pregnant or Nursing Women
While GHK-Cu is generally suitable for topical use, consult a healthcare professional before use during pregnancy or breastfeeding.
Individuals with Sensitive Skin
If you have highly sensitive skin, introduce the product gradually by using it every other night, or consult with a dermatologist for personalized advice.
People with Allergies to Copper Peptides
Those with known sensitivities or allergies to copper peptides should avoid using this product.
GHK-Cu is an endogenous occurring copper-binding tripeptide composed of glycine (G), histidine (H), and lysine (K). It has a high affinity for copper ions (Cu²⁺), forming a stable and biologically active complex that may support copper’s bioavailability and intracellular activity.2,3 This interaction is associated with several biological processes involved in maintaining skin health, collagen support, healthy hair, immune function, and angiogenesis (the formation of new blood vessels)1-3. Additionally, GHK-Cu is formulated to help address oxidative stress and support the skin's response to environmental factors.2,3
IMPORTANT INFORMATION ABOUT COMPOUNDED MEDICATIONS
This medication has been compounded (custom-prepared) by a pharmacy. Compounded medications are specially prepared for individual patient needs based on a valid prescription from a prescribing healthcare practitioner and, as such, are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. Compounded drugs are intended for patients whose prescriber has determined their medical needs are not met by an available FDA-approved drug. These statements have not been evaluated by the FDA.
This compounded preparation:
- Has not been approved by the FDA
- Has not undergone FDA review for safety, effectiveness, or quality
- Is prepared specifically for you based on your prescriber's order
- Individual outcomes may vary
Dosing is determined by the prescribing provider based on patient-specific factors. Always follow your healthcare provider's instructions. Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications. This medication should be prescribed and monitored by a licensed healthcare professional familiar with the condition being addressed and the specific applications of the medication.
1. Dou Y, Lee A, Zhu L, Morton J, Ladiges W. The potential of GHK as an anti-aging peptide. Aging Pathobiol Ther. 2020 Mar 27;2(1):58-61. doi:
10.31491/apt.2020.03.014. PMID: 35083444; PMCID: PMC8789089
2. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108. doi: 10.1155/2015/648108. Epub 2015 Jul 7. PMID: 26236730; PMCID: PMC4508379.
3. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987. doi: 10.3390/ijms19071987. PMID: 29986520; PMCID: PMC6073405.
This medication has been compounded (custom-prepared) by a pharmacy.
This compounded preparation:
- Has not been approved by the FDA
- Has not undergone FDA review for safety, effectiveness, or quality
- Is prepared specifically for you based on your prescriber's order
- Individual outcomes may vary
Disclaimer:
Compounded medications are specially prepared for individual patient needs based on a valid prescription and, as such, are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. These statements have not been evaluated by the FDA.
This information is for educational and informational purposes only. It is not medical advice or a health, diagnosis, or a treatment recommendation. Always consult your healthcare provider before starting any new medication to determine whether it is appropriate for your individual circumstances. Contact your healthcare provider with any questions regarding a medical condition.
Q: Is GHK-Cu Cream suitable for all skin types?
A: Yes, GHK-Cu is generally well tolerated, even with those with sensitive skin. However, people with very reactive or compromised skin should start with a patch test.
Q: Will this cream stain the skin blue?
A: No, not in the cream form. While it is blue in color, our well-formulated cream does not stain. If the color is strong, it usually fades quickly upon absorption.
Q: When will I see possible outcomes?
A: Outcomes will vary between patients. Some may notice changes in skin texture and hydration within 1–2 weeks, but collagen remodeling and deeper changes may take 4–12 weeks with consistent use.
Q: If GHK-Cu contains copper should I be worried about copper toxicity?
A: GHK-Cu uses a very small amount of copper, keeps it tightly bound in a peptide complex that inactivates its harmful free‑radical chemistry, and operates within the body’s normal copper‑handling pathways, so when used as directed it is not expected to meaningfully raise systemic copper levels in people with normal copper metabolism.
