GHK-Cu

Some of the potential benefits include but are not limited to:

• Anti-inflammatory effects
• Support tissue repair and wound healing
• Promote collagen synthesis for improved skin health
• Support hair growth
• Support new blood vessel formation
• Stimulate immune cell production
• Decrease cellular oxidative damage by neutralizing free radicals

Skin Sensitivity and Irritation

• Although generally well tolerated, some individuals may experience skin irritation or allergic reactions when using products containing GHK-Cu.
• If redness, itching, or swelling occurs, discontinue use and consult a healthcare provider.

Pregnancy

• Safety has not been established.

Pediatrics

• Safety has not been established

GHK-Cu is a naturally occurring copper-binding tripeptide composed of glycine (G), histidine (H), and lysine (K). It has a high affinity for copper ions (Cu²⁺), forming a stable and biologically active complex that enhances copper’s bioavailability and intracellular activity. This interaction is thought to activate key biological pathways involved in wound healing, collagen synthesis, hair growth, immune function, and angiogenesis (the formation of new blood vessels). Additionally, GHK-Cu may exhibit antioxidant and neuroprotective properties, further contributing to tissue repair and overall cellular health.

IMPORTANT INFORMATION ABOUT COMPOUNDED MEDICATIONS

This medication has been compounded (custom-prepared) by a pharmacy. Compounded medications are specially prepared for individual patient needs based on a valid prescription from a prescribing healthcare practitioner and, as such, are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. Compounded drugs are intended for patients whose prescriber has determined their medical needs are not met by an available FDA-approved drug. These statements have not been evaluated by the FDA.

This compounded preparation:

• Has not been approved by the FDA
• Has not undergone FDA review for safety, effectiveness, or quality
• Is prepared specifically for you based on your prescriber's order
• Individual outcomes may vary

Dosing is determined by the prescribing provider based on patient-specific factors. Always follow your healthcare provider's instructions. Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications. This medication should be prescribed and monitored by a licensed healthcare professional familiar with the condition being addressed and the specific applications of the medication.

Dou Y, Lee A, Zhu L, Morton J, Ladiges W. The potential of GHK as an anti-aging peptide. Aging Pathobiol Ther. 2020 Mar 27;2(1):58-61. doi:
10.31491/apt.2020.03.014. PMID: 35083444; PMCID: PMC8789089

Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108. doi: 10.1155/2015/648108. Epub 2015 Jul 7. PMID: 26236730; PMCID: PMC4508379.

Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987. doi: 10.3390/ijms19071987. PMID: 29986520; PMCID: PMC6073405.